Who poisoned a village by changing all the water into rotten grape juice?
Better question, who was the first person to drink wine? Or any new type of liquor, for that matter.
Then there's the whole matter of Christian sects that forbid alcohol altogether. I don't understand them at all-their own savior had no problem with social drinking. Not getting soused, yeah, but... their own top man said, aw, man, we have no wine for this banquet, just water? That'll never do. No problem, watch this...